A synergistic bactericidal effect of low-frequency and low-intensity ultrasound combined with levofloxacin-loaded PLGA nanoparticles on M. smegmatis in macrophages

A synergistic bactericidal effect of low-frequency and low-intensity ultrasound combined with levofloxacin-loaded PLGA nanoparticles on M. smegmatis in macrophages

Abstract Purpose Tuberculosis (TB) is a highly infectious disease caused by Mycobacterium tuberculosis (Mtb), which often parasites in macrophages. This study is performed to investigate the bactericidal effect and underlying mechanisms of low-frequency and low-intensity ultrasound (LFLIU) combined...

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Bibliographic Details
Main Authors: Shuang Xie, Gangjing Li, Yuru Hou, Min Yang, Fahui Li, Jianhu Li, Dairong Li, Yonghong Du
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Journal of Nanobiotechnology
Subjects:
Levofloxacin-loaded nanoparticles
Low-frequency and low-intensity ultrasound
Bactericidal effect
M. smegmatis
Macrophages
Online Access:http://link.springer.com/article/10.1186/s12951-020-00658-7

Internet

http://link.springer.com/article/10.1186/s12951-020-00658-7

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