The extracellular and intracellular regions of Crb2a play distinct roles in guiding the formation of the apical zonula adherens

The transmembrane protein Crumbs (Crb), a key regulator of apical polarity, has a known involvement in establishment of the apical zonula adherens in epithelia, although the precise mechanism remains elusive. The zonula adherens are required to maintain the integrity and orderly arrangement of epith...

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Bibliographic Details
Main Authors: Yuchen Lin, Kechao Weng, Jiancheng Liang, Yao Zhou, Qinlong Hao, Yumei Hao, Ke Yao, Jian Zou
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220301323