Tetradecylthioacetic acid inhibits proliferation of human SW620 colon cancer cells - gene expression profiling implies endoplasmic reticulum stress

Tetradecylthioacetic acid inhibits proliferation of human SW620 colon cancer cells - gene expression profiling implies endoplasmic reticulum stress

<p>Abstract</p> <p>Background</p> <p>Previous reports have shown an antiproliferative effect of the synthetic, 3-thia fatty acid tetradecylthioacetic acid (TTA) on different cancer cells <it>in vitro </it>and <it>in vivo</it>. The mechanisms behi...

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Bibliographic Details
Main Authors: Lundemo Anne G, Pettersen Caroline HH, Berge Kjetil, Berge Rolf K, Schønberg Svanhild A
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Lipids in Health and Disease
Subjects:
Cell cycle
Colon cancer
Docosahexaenoic acid
Endoplasmic reticulum stress
Gene expression analysis
Phosphorylated eIF2α
Tetradecylthioacetic acid
Thia fatty acids
Unfolded protein response
Online Access:http://www.lipidworld.com/content/10/1/190

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http://www.lipidworld.com/content/10/1/190

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