Huntingtin Aggregates in the Olfactory Bulb in Huntington’s Disease

Olfactory deficits are an early and prevalent non-motor symptom of Huntington’s disease (HD). In other neurodegenerative diseases where olfactory deficits occur, such as Alzheimer’s disease and Parkinson’s disease, pathological protein aggregates (tau, β-amyloid, α-synuclein) accumulate in the anter...

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Bibliographic Details
Main Authors: Blake Highet, Birger Victor Dieriks, Helen C. Murray, Richard L. M. Faull, Maurice A. Curtis
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Aging Neuroscience
Subjects:
tau
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2020.00261/full