Bi-directional actions of estrogen on the renin-angiotensin system

Bi-directional actions of estrogen on the renin-angiotensin system

Estrogen stimulates the renin-angiotensin system by augmenting both tissue and circulating levels of angiotensinogen and renin. We show, however, that angiotensin converting enzyme (ACE) activity in the circulation and in tissues is reduced in two animal models of postmenopausal chronic hormone repl...

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Bibliographic Details
Main Authors: K.B. Brosnihan, P.S. Senanayake, P. Li, C.M. Ferrario
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 1999-04-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
renin
angiotensin converting enzyme
angiotensin peptides
angiotensin receptors
bradykinin
nitric oxide
kinins
vasodilation
hormone replacement
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000400001

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000400001

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