The Contribution of Chemoattractant GPCRs, Formylpeptide Receptors, to Inflammation and Cancer

The Contribution of Chemoattractant GPCRs, Formylpeptide Receptors, to Inflammation and Cancer

A hallmark of inflammatory responses is leukocyte mobilization, which is mediated by pathogen and host released chemotactic factors that activate Gi-protein-coupled seven-transmembrane receptors (GPCRs) on host cell surface. Formylpeptide receptors (FPRs, Fprs in mice) are members of the chemoattrac...

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Bibliographic Details
Main Authors: Weiwei Liang, Keqiang Chen, Wanghua Gong, Teizo Yoshimura, Yingying Le, Ying Wang, Ji Ming Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Endocrinology
Subjects:
FPRs
regulation
chemotaxis
inflammation
infection
immunity
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00017/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2020.00017/full

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