Eculizumab in paroxysmal nocturnal hemoglobinuria with Budd-Chiari syndrome progressing despite anticoagulation

Eculizumab in paroxysmal nocturnal hemoglobinuria with Budd-Chiari syndrome progressing despite anticoagulation

<p>Abstract</p> <p>Paroxysmal nocturnal hemoglobinuria (PNH) is a progressive, life-threatening disorder characterized by chronic intravascular hemolysis caused by uncontrolled complement activation. Hepatic vein thrombosis (Budd-Chiari syndrome) is common in PNH patients. This cas...

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Bibliographic Details
Main Authors: Brodsky Andrés, Mazzocchi Octavio, Sánchez Fabiana, Khursigara Gus, Malhotra Suneil, Volpacchio Mariano
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Experimental Hematology & Oncology
Subjects:
Budd-Chiari syndrome
Complement inhibition
Eculizumab
Paroxysmal nocturnal hemoglobinuria
Online Access:http://www.ehoonline.org/content/1/1/26

Internet

http://www.ehoonline.org/content/1/1/26

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