Impaired Immune Response to Primary but Not to Booster Vaccination Against Hepatitis B in Older Adults

Many current vaccines are less immunogenic and less effective in elderly compared to younger adults due to age-related changes of the immune system. Most vaccines utilized in the elderly contain antigens, which the target population has had previous contact with due to previous vaccination or infect...

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Bibliographic Details
Main Authors: Birgit Weinberger, Mariëlle C. Haks, Roelof A. de Paus, Tom H. M. Ottenhoff, Tanja Bauer, Beatrix Grubeck-Loebenstein
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.01035/full