Coupling Aptamers to Short Interfering RNAs as Therapeutics

Coupling Aptamers to Short Interfering RNAs as Therapeutics

RNA-based approaches are among the most promising strategies aimed at developing safer and more effective therapeutics. RNA therapeutics include small non-coding miRNAs, small interfering RNA, RNA aptamers and more recently, small activating RNAs. However, major barriers exist to the use of RNAs as...

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Bibliographic Details
Main Authors: Vittorio de Franciscis, Laura Cerchia, Carla Lucia Esposito, Simona Camorani, Silvia Catuogno
Format: Article
Language:English
Published: MDPI AG 2011-10-01
Series:Pharmaceuticals
Subjects:
aptamer
intracellular delivery
microRNA
small interfering RNA
Online Access:http://www.mdpi.com/1424-8247/4/11/1434/

Internet

http://www.mdpi.com/1424-8247/4/11/1434/

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