A Native Human Monoclonal Antibody Targeting HCMV gB (AD-2 Site I)

A Native Human Monoclonal Antibody Targeting HCMV gB (AD-2 Site I)

Hyperimmune globulin (HIG) has shown efficacy against human cytomegalovirus (HCMV) for both transplant and congenital transmission indications. Replicating that activity with a monoclonal antibody (mAb) offers the potential for improved consistency in manufacturing, lower infusion volume, and improv...

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Bibliographic Details
Main Authors: Michael M. McVoy, Edgar Tenorio, Lawrence M. Kauvar
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:International Journal of Molecular Sciences
Subjects:
cytomegalovirus
cell tropism
conserved site
monoclonal antibody
neutralization
congenital transmission
immune suppression
Online Access:https://www.mdpi.com/1422-0067/19/12/3982

Internet

https://www.mdpi.com/1422-0067/19/12/3982

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