Epitope Mapping and Fine Specificity of Human T and B Cell Responses for Novel Candidate Blood-Stage Malaria Vaccine P27A

Epitope Mapping and Fine Specificity of Human T and B Cell Responses for Novel Candidate Blood-Stage Malaria Vaccine P27A

P27A is a novel synthetic malaria vaccine candidate derived from the blood stage Plasmodium falciparum protein Trophozoite Exported Protein 1 (TEX1/PFF0165c). In phase 1a/1b clinical trials in malaria unexposed adults in Switzerland and in malaria pre-exposed adults in Tanzania, P27A formulated with...

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Bibliographic Details
Main Authors: Kristina M. Geiger, Daniel Guignard, Che Yang, Jean-Pierre Bikorimana, Bruno E. Correia, Sophie Houard, Catherine Mkindi, Claudia A. Daubenberger, François Spertini, Giampietro Corradin, Régine Audran
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Immunology
Subjects:
malaria
Plasmodium falciparum
vaccine
P27A
clinical trial
immune response
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00412/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00412/full

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