An Improved 2-Aminoimidazole Based Anti-Biofilm Coating for Orthopedic Implants: Activity, Stability, and in vivo Biocompatibility

An Improved 2-Aminoimidazole Based Anti-Biofilm Coating for Orthopedic Implants: Activity, Stability, and in vivo Biocompatibility

Orthopedic device-related infections remain a serious challenge to treat. Central to these infections are bacterial biofilms that form on the orthopedic implant itself. These biofilms shield the bacteria from the host immune system and most common antibiotic drugs, which renders them essentially ant...

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Bibliographic Details
Main Authors: Guglielmo Attilio Coppola, Jolien Onsea, T. Fintan Moriarty, Dirk Nehrbass, Caroline Constant, Stephan Zeiter, Merve Kübra Aktan, Annabel Braem, Erik V. Van der Eycken, Hans P. Steenackers, Willem-Jan Metsemakers
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Microbiology
Subjects:
antibiofilm
titanium
implants
2-aminoimidazole
coating
Staphylococcus aureus
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.658521/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.658521/full

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