Protective Effect of Caffeic Acid on Paclitaxel Induced Anti-Proliferation and Apoptosis of Lung Cancer Cells Involves NF-κB Pathway

Protective Effect of Caffeic Acid on Paclitaxel Induced Anti-Proliferation and Apoptosis of Lung Cancer Cells Involves NF-κB Pathway

Caffeic acid (CA), a natural phenolic compound, is abundant in medicinal plants. CA possesses multiple biological effects such as anti-bacterial and anti-cancer growth. CA was also reported to induce fore stomach and kidney tumors in a mouse model. Here we used two human lung cancer cell lines, A549...

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Bibliographic Details
Main Authors: Yao Fong, Wen-Tsan Chang, Chang-Yi Wu, Chien-Chih Chiu, Wei-Chiao Chang, Ruei-Feng Chen, Jeff Yi-Fu Chen, Ying-Chieh Chu, Hui-Min Wang, Chien-Liang Lin, Han-Lin Chou
Format: Article
Language:English
Published: MDPI AG 2012-05-01
Series:International Journal of Molecular Sciences
Subjects:
caffeic acid
non-small cell lung cancer
paclitaxel
survivin
Bcl-2
NF-κB
Online Access:http://www.mdpi.com/1422-0067/13/5/6236

Internet

http://www.mdpi.com/1422-0067/13/5/6236

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