Designing a high-throughput somatic mutation profiling panel specifically for gynaecological cancers.

Designing a high-throughput somatic mutation profiling panel specifically for gynaecological cancers.

Somatic mutations play a major role in tumour initiation and progression. The mutation status of a tumour may predict prognosis and guide targeted therapies. The majority of techniques to study oncogenic mutations require high quality and quantity DNA or are analytically challenging. Mass-spectromet...

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Bibliographic Details
Main Authors: Vivian M Spaans, Marjolijn D Trietsch, Stijn Crobach, Ellen Stelloo, Dennis Kremer, Elisabeth M Osse, Natalja T ter Haar, Ronald van Eijk, Susanne Muller, Tom van Wezel, J Baptist Trimbos, Tjalling Bosse, Vincent T H B M Smit, Gert Jan Fleuren
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3966900?pdf=render

Internet

http://europepmc.org/articles/PMC3966900?pdf=render

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