New insights into an X-traordinary Viral Protein

New insights into an X-traordinary Viral Protein

Vpx is a protein encoded by members of the HIV-2/SIVsmm and SIVrcm/SIVmnd-2 lineages of primate lentiviruses, and which is packaged into viral particles. Vpx plays a critical role during the early steps of the viral life cycle and has been shown to counteract the SAMHD1 restriction factor in myeloid...

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Bibliographic Details
Main Authors: Torsten eSchaller, Hélène eBauby, Stéphane eHué, Michael H Malim, Caroline eGoujon
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Microbiology
Subjects:
HIV-1
HIV-2
Interferon Type I
Myeloid Cells
restriction factor
SAMHD1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00126/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00126/full

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