A Reverse Transcriptase-Dependent Mechanism Is Essential for Murine Preimplantation Development

A Reverse Transcriptase-Dependent Mechanism Is Essential for Murine Preimplantation Development

LINE-1 (Long Interspersed Nuclear elements) and HERVs (Human Endogenous Retroviruses) are two families of retrotransposons which together account for about 28% of the human genome. Genes harbored within LINE-1 and HERV retrotransposons, particularly that encoding the reverse transcriptase (RT) enzym...

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Bibliographic Details
Main Authors: Corrado Spadafora, Angela Curatolo, Ilaria Sciamanna, Patrizia Vitullo
Format: Article
Language:English
Published: MDPI AG 2011-05-01
Series:Genes
Subjects:
preimplantation embryo development
retrotransposon
LINE-1
reverse transcriptase inhibitors
tumorigenesis
Online Access:http://www.mdpi.com/2073-4425/2/2/360/

Internet

http://www.mdpi.com/2073-4425/2/2/360/

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