Melatonin promotes osteoblast differentiation by regulating Osterix protein stability and expression

Abstract Although the biological role of melatonin in osteogenic differentiation has been suggested, the mechanism of osteoblast differentiation remains unclear. Thus, the present study investigated the underlying molecular mechanisms based on osteoblast-specific transcription factors. We found that...

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Bibliographic Details
Main Authors: Younho Han, Young-Mi Kim, Hyung Sik Kim, Kwang Youl Lee
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06304-x