GDNF signaling in subjects with minimal motor deficits and Parkinson's disease

The failure of glial cell derived neurotropic factor to be efficacious in blinded clinical trials for Parkinson's disease may be due to alterations in signaling receptors and downstream signaling molecules. To test this hypothesis, brain sections were obtained from older adults with no motor de...

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Bibliographic Details
Main Authors: Yaping Chu, Jeffrey H. Kordower
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Neurobiology of Disease
Subjects:
RET
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121000474