Serum from patients with ankylosing spondylitis can increase PPARD, fra-1, MMP7, OPG and RANKL expression in MG63 cells

Serum from patients with ankylosing spondylitis can increase PPARD, fra-1, MMP7, OPG and RANKL expression in MG63 cells

OBJECTIVES: To explore the effects of serum from patients with ankylosing spondylitis on the canonical Wnt/β-catenin pathway and to assess whether the serum has an osteogenic effect in MG63 cells. METHODS: MG63 cells were cultured with serum from 45 ankylosing spondylitis patients, 30 healthy contr...

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Bibliographic Details
Main Authors: Zaiying Hu, Dongfang Lin, Jun Qi, Minli Qiu, Qing Lv, Qiuxia Li, Zhiming Lin, Zetao Liao, Yunfeng Pan, Ou Jin, Yuqiong Wu, Jieruo Gu
Format: Article
Language:English
Published: Faculdade de Medicina / USP 2015-11-01
Series:Clinics
Subjects:
Ankylosing Spondylitis
Wnt Pathway
Gene Expression
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322015001100738&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322015001100738&lng=en&tlng=en

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