A Genome-Wide Integrative Association Study of DNA Methylation and Gene Expression Data and Later Life Cognitive Functioning in Monozygotic Twins

A Genome-Wide Integrative Association Study of DNA Methylation and Gene Expression Data and Later Life Cognitive Functioning in Monozygotic Twins

Monozygotic twins are genetically identical but rarely phenotypically identical. Epigenetic and transcriptional variation could influence this phenotypic discordance. Investigation of intra-pair differences in molecular markers and a given phenotype in monozygotic twins controls most of the genetic...

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Bibliographic Details
Main Authors: Mette Soerensen, Dominika Marzena Hozakowska-Roszkowska, Marianne Nygaard, Martin J. Larsen, Veit Schwämmle, Kaare Christensen, Lene Christiansen, Qihua Tan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Neuroscience
Subjects:
later life cognitive functioning
epigenome-wide association study
transcriptome-wide association study
integrative
monozygotic twins
intra-pair comparison
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00233/full

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https://www.frontiersin.org/article/10.3389/fnins.2020.00233/full

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