Detection of newly produced T and B lymphocytes by digital PCR in blood stored dry on nylon flocked swabs

Abstract Background A normal number of T-cell receptor excision circles (TRECs) and K-deleting recombination excision circles (KRECs) is considered a biomarker for adequate new T- and B-cell production. In newborns, detection of TRECs and KRECs by real time PCR from dried blood spotted on filter pap...

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Bibliographic Details
Main Authors: Marion Vaglio Tessitore, Alessandra Sottini, Aldo M. Roccaro, Claudia Ghidini, Simona Bernardi, Giovanni Martellosio, Federico Serana, Luisa Imberti
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Journal of Translational Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12967-017-1169-9