BAG6 contributes to glucose uptake by supporting the cell surface translocation of the glucose transporter GLUT4

Defective translocation of glucose transporter 4 (GLUT4) to the cell surface is a key feature of insulin resistance in type 2 diabetes. Therefore, elucidating the mechanism of GLUT4 translocation is of primary importance. The mammalian Bag6/Bat3 gene has been suggested to be linked with potential ob...

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Bibliographic Details
Main Authors: Setsuya Minami, Naoto Yokota, Hiroyuki Kawahara
Format: Article
Language:English
Published: The Company of Biologists 2020-01-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/9/1/bio047324