Immunogenicity and Neutralizing Activity Comparison of SARS-CoV-2 Spike Full-Length and Subunit Domain Proteins in Young Adult and Old-Aged Mice

Immunogenicity and Neutralizing Activity Comparison of SARS-CoV-2 Spike Full-Length and Subunit Domain Proteins in Young Adult and Old-Aged Mice

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to be expanding the pandemic disease across the globe. Although SARS-CoV-2 vaccines were rapidly developed and approved for emergency use of vaccination in humans, supply and production difficulties are slowing down the global va...

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Bibliographic Details
Main Authors: Ki-Hye Kim, Noopur Bhatnagar, Subbiah Jeeva, Judy Oh, Bo Ryoung Park, Chong Hyun Shin, Bao-Zhong Wang, Sang-Moo Kang
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Vaccines
Subjects:
SARS-CoV-2
spike
neutralizing activity
RBD-hACE2 inhibition
cellular immunity
aged mice
Online Access:https://www.mdpi.com/2076-393X/9/4/316

Internet

https://www.mdpi.com/2076-393X/9/4/316

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