Lower expression of inducible nitric oxide synthase and higher expression of arginase in rat alveolar macrophages are linked to their susceptibility to Toxoplasma gondii infection.

Lower expression of inducible nitric oxide synthase and higher expression of arginase in rat alveolar macrophages are linked to their susceptibility to Toxoplasma gondii infection.

Rats are naturally resistant to Toxoplasma gondii infection, particularly the RH strain, while mice are not. Previous studies have demonstrated that inducible nitric oxide synthase (iNOS) and arginase-1 of rodent peritoneal macrophages are linked to the mechanism of resistance. As an increasing numb...

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Bibliographic Details
Main Authors: Zhi-Jun Zhao, Jia Zhang, Jun Wei, Zhi Li, Tao Wang, Si-Qi Yi, Ji-Long Shen, Ting-Bao Yang, Geoff Hide, Zhao-Rong Lun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23691079/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23691079/?tool=EBI

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