MITF reprograms the extracellular matrix and focal adhesion in melanoma

MITF reprograms the extracellular matrix and focal adhesion in melanoma

The microphthalmia-associated transcription factor (MITF) is a critical regulator of melanocyte development and differentiation. It also plays an important role in melanoma where it has been described as a molecular rheostat that, depending on activity levels, allows reversible switching between dif...

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Bibliographic Details
Main Authors: Ramile Dilshat, Valerie Fock, Colin Kenny, Ilse Gerritsen, Romain Maurice Jacques Lasseur, Jana Travnickova, Ossia M Eichhoff, Philipp Cerny, Katrin Möller, Sara Sigurbjörnsdóttir, Kritika Kirty, Berglind Ósk Einarsdottir, Phil F Cheng, Mitchell Levesque, Robert A Cornell, E Elizabeth Patton, Lionel Larue, Marie de Tayrac, Erna Magnúsdóttir, Margrét Helga Ögmundsdóttir, Eirikur Steingrimsson
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-01-01
Series:eLife
Subjects:
melanoma
extracellular matrix
MITF
focal adhesion
repression
Online Access:https://elifesciences.org/articles/63093

Internet

https://elifesciences.org/articles/63093

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