Selection, affinity maturation, and characterization of a human scFv antibody against CEA protein

Selection, affinity maturation, and characterization of a human scFv antibody against CEA protein

<p>Abstract</p> <p>Background</p> <p>CEA is a tumor-associated antigen abundantly expressed on several cancer types, including those naturally refractory to chemotherapy. The selection and characterization of human anti-CEA single-chain antibody fragments (scFv) is a fi...

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Bibliographic Details
Main Authors: De Santis Rita, Monteriù Giorgia, Ascione Alessandro, Vaccaro Paola, D'Alessio Valeria, Pelliccia Angela, Anastasi Anna Maria, Petronzelli Fiorella, Barca Stefano, Dupuis Maria Luisa, Flego Michela, Pavoni Emiliano, Felici Franco, Cianfriglia Maurizio, Minenkova Olga
Format: Article
Language:English
Published: BMC 2006-02-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/6/41

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http://www.biomedcentral.com/1471-2407/6/41

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