The role of renal proximal tubule transport in the regulation of blood pressure

The electrogenic sodium/bicarbonate cotransporter 1 (NBCe1) on the basolateral side of the renal proximal tubule plays a pivotal role in systemic acid-base homeostasis. Mutations in the gene encoding NBCe1 cause severe proximal renal tubular acidosis accompanied by other extrarenal symptoms. The pro...

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Bibliographic Details
Main Authors: Shoko Horita, Motonobu Nakamura, Masashi Suzuki, Nobuhiko Satoh, Atsushi Suzuki, Yukio Homma, Masaomi Nangaku
Format: Article
Language:English
Published: The Korean Society of Nephrology 2017-03-01
Series:Kidney Research and Clinical Practice
Subjects:
Online Access:https://doi.org/10.23876/j.krcp.2017.36.1.12