Concentration-dependent exchange of replication protein A on single-stranded DNA revealed by single-molecule imaging.

Replication protein A (RPA) is a ubiquitous eukaryotic single-stranded DNA (ssDNA) binding protein necessary for all aspects of DNA metabolism involving an ssDNA intermediate, including DNA replication, repair, recombination, DNA damage response and checkpoint activation, and telomere maintenance. T...

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Bibliographic Details
Main Authors: Bryan Gibb, Ling F Ye, Stephanie C Gergoudis, YoungHo Kwon, Hengyao Niu, Patrick Sung, Eric C Greene
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3912175?pdf=render