Honokiol enhances paclitaxel efficacy in multi-drug resistant human cancer model through the induction of apoptosis.

Honokiol enhances paclitaxel efficacy in multi-drug resistant human cancer model through the induction of apoptosis.

Resistance to chemotherapy remains a major obstacle in cancer therapy. This study aimed to evaluate the molecular mechanism and efficacy of honokiol in inducing apoptosis and enhancing paclitaxel chemotherapy in pre-clinical multi-drug resistant (MDR) cancer models, including lineage-derived human M...

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Bibliographic Details
Main Authors: Xu Wang, Jonathan J Beitler, Hong Wang, Michael J Lee, Wen Huang, Lydia Koenig, Sreenivas Nannapaneni, A R M Ruhul Amin, Michael Bonner, Hyung Ju C Shin, Zhuo Georgia Chen, Jack L Arbiser, Dong M Shin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3934844?pdf=render

Internet

http://europepmc.org/articles/PMC3934844?pdf=render

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