Chromatin remodeller Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation

Nucleosomes have been shown to impede the elongation of RNA polymerase II during transcription. Here, the authors provide evidence that in fission yeast chromatin remodeller Fun30Fft3 localizes to transcribing regions to promote transcription by nucleosome disassembly in vivo.

Bibliographic Details
Main Authors: Junwoo Lee, Eun Shik Choi, Hogyu David Seo, Keunsoo Kang, Joshua M. Gilmore, Laurence Florens, Michael P. Washburn, Joonho Choe, Jerry L. Workman, Daeyoup Lee
Format: Article
Language:English
Published: Nature Publishing Group 2017-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14527