Translational approach for gene therapy in epilepsy: Model system and unilateral overexpression of neuropeptide Y and Y2 receptors

Although novel treatment strategies based on the gene therapy approach for epilepsy has been encouraging, there is still a gap in demonstrating a proof-of-concept in a clinically relevant animal model and study design. In the present study, a conceptually novel framework reflecting a plausible clini...

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Bibliographic Details
Main Authors: Litsa Nikitidou Ledri, Esbjörn Melin, Søren H. Christiansen, Casper R. Gøtzsche, Alessandra Cifra, David P.D. Woldbye, Mérab Kokaia
Format: Article
Language:English
Published: Elsevier 2016-02-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996115300929