Identification of potent natural compounds in targeting Leishmania major CYP51 and GP63 proteins using a high-throughput computationally enhanced screening

Identification of potent natural compounds in targeting Leishmania major CYP51 and GP63 proteins using a high-throughput computationally enhanced screening

Abstract Background Leishmaniasis is a disease caused by protozoan forms called Leishmania which infect animals and humans. The drugs have been in use since half a century due to which there have been mutations in the microbe-facilitating drug resistance. So this provides a reason for searching for...

Full description

Bibliographic Details
Main Authors: Deepak A. Yaraguppi, Sanjay H. Deshpande, Zabin K. Bagewadi, Uday Muddapur, Sushil Anand, Santosh B. Patil
Format: Article
Language:English
Published: SpringerOpen 2020-06-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Leishmaniasis
Similarity indexing
Molecular docking
Drug design
Natural compounds
Online Access:http://link.springer.com/article/10.1186/s43094-020-00038-w

Internet

http://link.springer.com/article/10.1186/s43094-020-00038-w

Similar Items