The prognostic role of IDH mutations in homogeneously treated patients with anaplastic astrocytomas and glioblastomas

The prognostic role of IDH mutations in homogeneously treated patients with anaplastic astrocytomas and glioblastomas

Abstract The detection of IDH mutations in patients with diffusely infiltrating malignant astrocytomas resulted in substantial modifications in the concept of WHO classification of these tumors. An important underlying observation was that patients with anaplastic astrocytomas (AA) without IDH mutat...

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Bibliographic Details
Main Authors: Arne Christians, Antonia Adel-Horowski, Rouzbeh Banan, Ulrich Lehmann, Stephan Bartels, Felix Behling, Alonso Barrantes-Freer, Christine Stadelmann, Veit Rohde, Florian Stockhammer, Christian Hartmann
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Acta Neuropathologica Communications
Subjects:
IDH1
IDH2
MGMT
EGFR
Prognosis
Grading
Online Access:http://link.springer.com/article/10.1186/s40478-019-0817-0

Internet

http://link.springer.com/article/10.1186/s40478-019-0817-0

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