Crystal structure of Mokola virus glycoprotein in its post-fusion conformation.

Mokola virus (MOKV) belongs to the lyssavirus genus. As other genus members-including rabies virus (RABV)-it causes deadly encephalitis in mammals. MOKV entry into host cells is mediated by its transmembrane glycoprotein G. First, G binds cellular receptors, triggering virion endocytosis. Then, in t...

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Bibliographic Details
Main Authors: Laura Belot, Malika Ouldali, Stéphane Roche, Pierre Legrand, Yves Gaudin, Aurélie A Albertini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-03-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008383