Clinical Relevance and Immunosuppressive Pattern of Circulating and Infiltrating Subsets of Myeloid-Derived Suppressor Cells (MDSCs) in Epithelial Ovarian Cancer

Clinical Relevance and Immunosuppressive Pattern of Circulating and Infiltrating Subsets of Myeloid-Derived Suppressor Cells (MDSCs) in Epithelial Ovarian Cancer

Myeloid-derived suppressor cells (MDSCs) expansion is a hallmark of cancer. Three major MDSC subsets defined as monocytic (M)-MDSCs, polymorphonuclear (PMN)-MDSCs and early stage (e)MDSCs can be revealed in human diseases. However, the clinical relevance and immunosupressive pattern of these cells i...

Full description

Bibliographic Details
Main Authors: Karolina Okła, Arkadiusz Czerwonka, Anna Wawruszak, Marcin Bobiński, Monika Bilska, Rafał Tarkowski, Wiesława Bednarek, Iwona Wertel, Jan Kotarski
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
epithelial ovarian cancer
myeloid-derived suppressor cells
immunosuppression
prognosis
liquid biopsy
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00691/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00691/full

Similar Items