In Vivo and In Vitro Study of a Polylactide-Fiber-Reinforced β-Tricalcium Phosphate Composite Cage in an Ovine Anterior Cervical Intercorporal Fusion Model

A poly-70L/30DL-lactide (PLA70)–β-tricalcium phosphate (β-TCP) composite implant reinforced by continuous PLA-96L/4D-lactide (PLA96) fibers was designed for in vivo spinal fusion. The pilot study was performed with four sheep, using titanium cage implants as controls. The composite implants failed t...

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Bibliographic Details
Main Authors: Janek Frantzén, Aliisa Pälli, Esa Kotilainen, Harri Heino, Bettina Mannerström, Heini Huhtala, Hannu Kuokkanen, George K. Sándor, Kari Leino, Matias Röyttä, Riitta Parkkola, Riitta Suuronen, Susanna Miettinen, Hannu T. Aro, Suvi Haimi
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:International Journal of Biomaterials
Online Access:http://dx.doi.org/10.1155/2011/109638