Emulsified nanoparticles containing inactivated influenza virus and CpG oligodeoxynucleotides critically influences the host immune responses in mice.

<h4>Background</h4>Antigen sparing and cross-protective immunity are regarded as crucial in pandemic influenza vaccine development. Both targets can be achieved by adjuvantation strategy to elicit a robust and broadened immune response. We assessed the immunogenicity of an inactivated H5...

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Main Authors: Ming-Hsi Huang, Su-Chen Lin, Chia-Hsin Hsiao, Hsin-Ju Chao, Hung-Ren Yang, Chien-Chun Liao, Po-Wei Chuang, Huang-Pi Wu, Chiung-Yi Huang, Chih-Hsiang Leng, Shih-Jen Liu, Hsin-Wei Chen, Ai-Hsiang Chou, Alan Yung-Chih Hu, Pele Chong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20808862/?tool=EBI