Enolase and dipeptidyl peptidase IV protein sub-unit vaccines are not protective against a lethal Streptococcus suis serotype 2 challenge in a mouse model of infection

Enolase and dipeptidyl peptidase IV protein sub-unit vaccines are not protective against a lethal Streptococcus suis serotype 2 challenge in a mouse model of infection

Abstract Background Streptococcus suis is a major swine pathogen causing arthritis, meningitis and sudden death in post-weaning piglets and is also a zoonotic agent. S. suis comprises 35 different serotypes of which the serotype 2 is the most prevalent in both pigs and humans. In the absence of comm...

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Bibliographic Details
Main Authors: Audrey Dumesnil, Léa Martelet, Daniel Grenier, Jean-Philippe Auger, Josée Harel, Eric Nadeau, Marcelo Gottschalk
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Veterinary Research
Subjects:
Streptococcus suis serotype 2
Sub-unit vaccines
Antibody production
Protection
Mouse model
Experimental design, bias
Online Access:https://doi.org/10.1186/s12917-019-2196-y

Internet

https://doi.org/10.1186/s12917-019-2196-y

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