Striatal DAT and extrastriatal SERT binding in early-stage Parkinson's disease and dementia with Lewy bodies, compared with healthy controls: An 123I-FP-CIT SPECT study

Parkinson's disease (PD) and dementia with Lewy bodies (DLB) are thought to be part of a spectrum: both have a clinical profile including symptoms associated with dopaminergic and serotonergic loss, yet few imaging studies have focused on serotonergic neurodegeneration in both disorders. We aim...

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Bibliographic Details
Main Authors: Merijn Joling, Chris Vriend, Pieter G.H.M. Raijmakers, Jessica J. van der Zande, Afina W. Lemstra, Henk W. Berendse, Jan Booij, Odile A. van den Heuvel
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:NeuroImage: Clinical
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158219301056