Role of integrin alpha8 in murine model of lung fibrosis.

BACKGROUND:Integrin α8 (ITGA8) heterodimerizes with integrin β1 and is highly expressed in stromal cells of the lung. Platelet-derived growth factor receptor beta (PDGFRβ+) cells constitute a major population of contractile myofibroblasts in the lung following bleomycin-induced fibrosis. Integrin α8...

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Bibliographic Details
Main Authors: Chi F Hung, Carole L Wilson, Yu-Hua Chow, Lynn M Schnapp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5973593?pdf=render