Association between the nucleosome footprint of plasma DNA and neoadjuvant chemotherapy response for breast cancer

Abstract Gene expression signatures have been used to predict the outcome of chemotherapy for breast cancer. The nucleosome footprint of cell-free DNA (cfDNA) carries gene expression information of the original tissues and thus may be used to predict the response to chemotherapy. Here we carried out...

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Bibliographic Details
Main Authors: Xu Yang, Geng-Xi Cai, Bo-Wei Han, Zhi-Wei Guo, Ying-Song Wu, Xiaoming Lyu, Li-Min Huang, Yuan-Bin Zhang, Xin Li, Guo-Lin Ye, Xue-Xi Yang
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-021-00237-5