Selective leptin insensitivity and alterations in female-reproductive patterns linked to hyperleptinemia during infancy.

The dramatic increase in the prevalence of childhood obesity worldwide makes the investigation of its early developmental stages and effective prevention strategies an urgent issue. CCK1 deficient OLETF rats are a model of obesity previously used to study the early phases of this disorder. Here, we...

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Bibliographic Details
Main Authors: Mariana Schroeder, Noga Kronfeld-Schor, Aron Weller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3609828?pdf=render