Peripheral neutrophil functions and cell signalling in Crohn`s disease.

The role of the innate immunity in the pathogenesis of Crohn's disease (CD), an inflammatory bowel disease, is a subject of increasing interest. Neutrophils (PMN) are key members of the innate immune system which migrate to sites of bacterial infection and initiate the defence against microbes...

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Bibliographic Details
Main Authors: Rajesh Somasundaram, Veerle J A A Nuij, C Janneke van der Woude, Ernst J Kuipers, Maikel P Peppelenbosch, Gwenny M Fuhler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24367671/pdf/?tool=EBI