Molecular effects of doxycycline treatment on pterygium as revealed by massive transcriptome sequencing.

Pterygium is a lesion of the eye surface which involves cell proliferation, migration, angiogenesis, fibrosis, and extracellular matrix remodelling. Surgery is the only approved method to treat this disorder, but high recurrence rates are common. Recently, it has been shown in a mouse model that tre...

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Bibliographic Details
Main Authors: Ignacio M Larráyoz, Alberto de Luis, Oscar Rúa, Sara Velilla, Juan Cabello, Alfredo Martínez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3378547?pdf=render