Eugenol inhibits the GABAA current in trigeminal ganglion neurons.

Eugenol has sedative, antioxidant, anti-inflammatory, and analgesic effects, but also serves as an irritant through the regulation of a different set of ion channels. Activation of gamma aminobutyric acid (GABA) receptors on sensory neurons leads to the stabilization of neuronal excitability but con...

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Bibliographic Details
Main Authors: Sang Hoon Lee, Jee Youn Moon, Sung Jun Jung, Jin Gu Kang, Seung Pyo Choi, Jun Ho Jang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4311912?pdf=render