Niacin Inhibits Vascular Inflammation via Downregulating Nuclear Transcription Factor-κB Signaling Pathway

The study aimed to investigate the effect of niacin on vascular inflammatory lesions in vivo and in vitro as well as its lipid-regulating mechanism. In vivo study revealed that niacin downregulated the levels of inflammatory factors (IL-6 and TNF-α) in plasma, suppressed protein expression of CD68 a...

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Bibliographic Details
Main Authors: Yanhong Si, Ying Zhang, Jilong Zhao, Shoudong Guo, Lei Zhai, Shutong Yao, Hui Sang, Nana Yang, Guohua Song, Jue Gu, Shucun Qin
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2014/263786