Recombinant human IL-37 inhibited endometriosis development in a mouse model through increasing Th1/Th2 ratio by inducing the maturation of dendritic cells

Recombinant human IL-37 inhibited endometriosis development in a mouse model through increasing Th1/Th2 ratio by inducing the maturation of dendritic cells

Abstract Background Endometriosis is a serious reproductive and general health consequences. Recombinant human IL-37 (rhIL-37) is an inhibitor of inflammation. Methods ELISA assay was performed to detect the concentration of cytokines. Flow cytometry was used to analyze cell proportion. Besides, qRT...

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Bibliographic Details
Main Authors: Lijie Li, Zhouzhou Liao, Mingzhu Ye, Jianfa Jiang
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Reproductive Biology and Endocrinology
Subjects:
Endometriosis
Recombinant human IL-37
Dendritic cell
T cell differentiation
Online Access:https://doi.org/10.1186/s12958-021-00811-3

Internet

https://doi.org/10.1186/s12958-021-00811-3

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