Schwann cell expressed Nogo-B modulates axonal branching of adult sensory neurons through the Nogo-B receptor NgBR

Schwann cell expressed Nogo-B modulates axonal branching of adult sensory neurons through the Nogo-B receptor NgBR

In contrast to the central nervous system (CNS) nerve fibers do regenerate in the peripheral nervous system (PNS) although in a clinically unsatisfying manner. A major problem is excessive sprouting of regenerating axons which results in aberrant reinnervation of target tissue and impaired functiona...

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Bibliographic Details
Main Authors: Christoph eEckharter, Nina eJunker, Lilli eWinter, Irmgard eFischer, Barbara eFogli, Steffen eKistner, Kristian ePfaller, Binhai eZheng, Gerhard eWiche, Lars eKlimaschewski, Rüdiger eSchweigreiter
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Schwann Cells
Sciatic Nerve
receptor
sensory neurons
morphology
Nogo
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00454/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00454/full

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