Determination of the pH Gradient in Hair Follicles of Human Volunteers Using pH-Sensitive Melamine Formaldehyde-Pyranine Nile Blue Microparticles

Determination of the pH Gradient in Hair Follicles of Human Volunteers Using pH-Sensitive Melamine Formaldehyde-Pyranine Nile Blue Microparticles

Nanoparticles can be applied to the hair follicles, which can serve as reservoirs for triggered drug release. A valid measurement method for the determination of the pH within the hair follicle in vivo has not been shown yet. Here, melamine formaldehyde particles up to 9 µm in size were applied on 4...

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Bibliographic Details
Main Authors: Dennis Kaden, Lars Dähne, Fanny Knorr, Heike Richter, Jürgen Lademann, Martina C. Meinke, Alexa Patzelt, Maxim E. Darvin, Sora Jung
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Sensors
Subjects:
triggered drug release
follicular penetration
skin barrier
skin acidity
Online Access:https://www.mdpi.com/1424-8220/20/18/5243

Internet

https://www.mdpi.com/1424-8220/20/18/5243

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