Comparative transcriptome analysis unveils the adaptative mechanisms of Scedosporium apiospermum to the microenvironment encountered in the lungs of patients with cystic fibrosis

Comparative transcriptome analysis unveils the adaptative mechanisms of Scedosporium apiospermum to the microenvironment encountered in the lungs of patients with cystic fibrosis

Scedosporium species rank second among the filamentous fungi colonizing the lungs of patients with cystic fibrosis (CF). Apart from the context of immunodeficiency (lung transplantation), the colonization of the CF airways by these fungi usually remains asymptomatic. Why the colonization of the lowe...

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Bibliographic Details
Main Authors: Patrick Vandeputte, Thomas Dugé de Bernonville, Yohann Le Govic, Solène Le Gal, Gilles Nevez, Nicolas Papon, Jean-Philippe Bouchara
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Scedosporium apiospermum
Cystic fibrosis
Adaptation
Plasma membrane
Secondary metabolites
Degradation of aromatic compounds
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037020304566

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http://www.sciencedirect.com/science/article/pii/S2001037020304566

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